Loeffler H, Bieda A, Sombetzki M, Fischer RJ, Basen M, Schulz K, Waletzko J, Bader R, Klinder A. 2026.
Combined high hydrostatic pressure and additive chemical treatment enhances decontamination efficiency in bone tissue infected with
staphylococcal biofilms. Microorganisms (accepted for publication)

Loeffler H, Waletzko-Hellwig J, Fischer R-J, Basen M, Frank M, Jonitz-Heincke A, Bader R, Klinder A. 2024. Systematic enhancement of microbial decontamination efficiency in bone graft processing by means of high hydrostatic pressure using Escherichia coli as a model organism. J Biomed Mater Res 112:e35383. https://doi.org/10.1002/jbm.b.35383
 

Breitkopf, R., R. Uhlig, T. Drenckhan, R.-J. Fischer. 2016. Two propanediol utilization-like proteins of Moorella thermoacetica with phosphotransacetylase activity. Extremophiles. DOI: 10.1107/s00792-016-0854-6

Uhlig, R., A. Poehlein, R.-J. Fischer, R. Daniel, H. Bahl. 2016. Genome sequence of the autotrophic acetogen Clostridium magnum DSM 2767. Genome Announc 4(3): e00464-16. DOI: 10.1128/genomeA.00464-16

Hoffmeister, S., M. Gerdom, F. R. Bengelsdorf, S. Linder, S. Flüchter, H. Öztürk, W. Blümke, A. May, R.-J. Fischer, H. Bahl, P. Dürre. 2016. Acetone production with metabolically engineered srains of Acetobacterium woodii. Metabolic Engineering 36:37-47. DOI: 10.1016/j.ymben.2016.03.001

Wetzel, D., R.-J. Fischer. 2015. Small acid-soluble spore proteins of Clostridium acetobutylicum are able to protect DNA in vitro and are specifically cleaved by germination protease GPR and spore protease YyaC . Microbiology 161:2098-2109 DOI: 10.1099/mic.0.000162.

Millat, T., C. Voigt, H. Janssen, C. M. Cooksley, K. Winzer, N. P. Minton, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2014. Coenzyme A-transferase-independent butyrate reassimilation in Clostridium acetobutylicum - evidence from a mathematical model. Appl Microbiol Biotechnol 98:9059-9072 DOI: 10.1007/s00253-014-5987-x

Voigt,C., H. Bahl, R.-J. Fischer. 2014. Identification of PTS^Fru as the major fructose uptake system of Clostridium acetobutylicum. Appl Microbiol Biotechnol 98:7161-7172 DOI: 10.1007/s00253-014-5809-1
 

Millat, T., H. Janssen, G. J. Thorn, J. R. King, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2013. A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicum in phosphate-limited continuous cultures. Appl Microbiol Biotechnol 97:6451-6466 DOI: 10.1007/s00253-013-4860-7

Millat, T., H. Janssen, H. Bahl, R.-J. Fischer, O. Wolkenhuer. 2013. The pH-induced metabolic shift from acidogenesis to solventogenesis in Clostridium acetobutlicum - From experiments to models. In: Kettner, C. and Hicks, M. G., eds., Proceedings of the 5th International Beilstein Symposium on Experimental Standard Condtions of Enzyme Characterizations Logos Verlag Berlin. 33-53.

Millat, T., H. Janssen, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2013. Integrative modelling of pH-dependent enzyme activity and transcriptomic regulation of the acetone-butanol-ethanol fermentation of Clostridium acetobutylicum in continous culture. Microbial Biotechnology, DOI: 10.1111/1751-7915.12033

May, A., R.-J. Fischer, S. M. Thum, S. Schaffer, S. Verseck, P. Dürre, H. Bahl. 2013. A modified pathway for the production of acetone in Escherichia coli. Metabolic Engineering 15: 218-225 http://dx.doi.org/10.1016/j.ymben.2012.08.001

Janssen, H., T. Fiedler, K. Schwarz, H.Bahl, R.-J. Fischer. 2012. Supporting systems biology of Clostridium acetobutylicum by proteome analysis. In: Systems Biology of Clostridium. (P. Dürre, Ed.), Imperial College Press., 56-84

Janssen, H., C. Grimmler, A. Ehrenreich, H. Bahl, R.-J. Fischer. 2012. A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum - Solvent stress caused by a transient n-butanol pulse. J Biotec. http://dx.doi.org/10.1016/j.jbiotec.2012.03.027

Haus, S., S. Jabbari, T. Millat, H. Janssen, R.-J. Fischer, H. Bahl, J. R. King, O. Wolkenhauer. 2011. A Systems Biology Approach to Investigate the Effect of pH-induced Gene Regulation on Solvent Production by Clostridium acetobutylicum in Continous Culture. BMC Systems Biology 5:10 (DOI:10.1186/1752-0509-5-10)

Millat, T., O. Wolkenhauer, R.-J. Fischer, H. Bahl. 2011. Modeling of Cellular Processes: Methods, Data, and Requirements. In: M. Hamacher et al. (eds.), Data Mining in Proteomics: From Standards to Applications, Methods in Molecular Biology, Vol. 696, DOI 10.1007/978-1-60761-987-1_27, Springer Science+Business Media, LLC 2011

Grimmler, C., H. Janssen, D. Krauße, R.-J. Fischer, H. Bahl, P. Dürre, W. Liebl, A. Ehrenreich. 2011: Genome-wide Gene Expression Analysis of the Switch between Acidogenesis and Solventogenesis in Continuous Cultures of Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol., 20:1-15 (DOI: 10.1159/000320973)

Janssen, H., C. Döring, A. Ehrenreich, B. Voigt, M. Hecker, H. Bahl, R.-J. Fischer. 2010: A proteomic and transcriptional view of acidogenic and solventogenic steady state cells of Clostridium acetobutylicum in a chemostat culture. Appl. Microbiol. Biotechnol., 87: 2209

Hillmann, F., Döring, C., Ehrenreich, A., Fischer, R.-J., Bahl, H. 2009. The role of PerR in O₂ affected gene expression of Clostridium acetobutylicum. J. Bacteriol., 191: 6082-6093

Hillmann, F., Riebe, O., Fischer, R.-J., Mot, A., Caranto, J. D., Kurtz, Jr., D. M., Bahl. H. 2009. Reductive dioxygen scavenging by flavo-diiron proteins of Clostridium acetobutylicum.
FEBS Lett. 583:241-245

Riebe, O., R.-J. Fischer, D. A. Wampler, D. M. Kurtz, Jr., H. Bahl. 2009. Pathway for H₂O₂ and O₂ detoxification in Clostridium acetobutylicum. Microbiology 155:16-24

Fiedler, T., M. Mix, U. Meyer, S. Mikkat, M. O. Glocker, H. Bahl, R.-J. Fischer. 2008. The two component system PhoP/R of Clostridium acetobutylicum is involved in phosphate dependent gene
regulation. J. Bacteriol. 190: 6559-6567

Harndorf, H., B. Bahl, R.-J. Fischer, E. Flügge, U. Schümann, V. Wichmann. 2008. Untersuchungen der Mutagenität von Motorabgasen an einem Euro IIIa Traktormotor im Diesel-, Biodiesel-, und Rapsölbetrieb. Raps 4/2008: 212-214

Hillmann, F., Fischer, R.-J., Saint-Prix, F., Girbal, L., Bahl, H. 2008. PerR acts as a switch for oxygen tolerance in the strict anaerobe Clostridium acetobutylicum. Mol. Microbiol. 68: 848-860

Riebe, O., Fischer, R.-J., Bahl, H. 2007. Desulfoferrodoxin of Clostridium acetobutylicum functions as a superoxide reductase. FEBS Lett. 581: 5605-5610

Schwarz, K., T. Fiedler, R.-J. Fischer, H. Bahl. 2007. A Standard Operating Procedure (SOP) for the preparation of intra- and extracellular proteins of Clostridium acetobutylicum for proteome analysis. J. Microbiol. Meth. 68: 396-402

Fischer, R.-J., Oehmcke, S., Meyer, U., Mix, M., Schwarz, K., Fiedler, T., Bahl, H. 2006. Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH. J. Bacteriol. 188: 5469-5478

Hillmann, F., Fischer, R.-J., Bahl, H. 2006. The rubrerythrin-like protein Hsp21 of Clostridium acetobutylicum is a general stress protein. Arch. Microbiol.185 (4): 270-276

May, A., T. Pusztahelyi, N. Hoffmann, R.-J. Fischer, H. Bahl. 2006. Site-directed mutagenesis of conserved amino acids in SLH domains of Thermoanaerobacterium thermosulfurigenes EM1 effects attachment to cell wall sacculi. Arch. Microbiol.185 (4): 263-269

Fischer, R.-J., Bahl, H. 2005. Transport of phosphate. In: Dürre, P. (Ed.). Handbook on Clostridia. CRC Press, Boca Raton, Florida, USA.

May, A., Hillmann, F., Riebe, O., Fischer, R.-J., Bahl, H. 2004. A rubrerythrin-like oxidative stress protein of Clostridium acetobutylicum is encoded by a duplicated gene and identical to the heat shock protein Hsp21. FEMS Microbiol. Lett. 238: 249-254

Behrens, S., U. Meyer, H. Schankin, M. A. Lonetto, R.-J. Fischer, H. Bahl. 2000. Identification of two genes encoding putative new members of the ECF subfamily of eubacterial RNA polymerase sigma factors in Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol. 2(3): 265-269

Dürre, P., R.-J. Fischer, A. Kuhn, K. Lorenz, W. Schreiber, B. Stürzenhofecker, S. Ullmann, K. Winzer und U. Sauer. 1995. Solventogenic enzymes of Clostridium acetobutylicum: Catalytic properties, genetic organization, and transcriptional regulation. FEMS Microbiol. Rev. 17: 251-262.

Fischer, R.-J., U. Sauer und P. Dürre. 1994. Regulation of solvent formation in Clostridium acetobutylicum. In: Progress in Biotechnology 9, ECB6: Proceedings of the 6th European Congress on Biotechnology, Florence, Italy, June 13-17, 1993 (L. Alberghina, L. Frontali, P. Sensi, Hrsg.), Elsevier Science B. V., Amsterdam. S. 337-340.

Fischer, R.-J. 1994. Klonierung, Sequenzierung, molekulare Charakterisierung und Mutagenese von Genen der Lösungsmittelbildung aus Clostridium acetobutylicum. Dissertation, Universität Göttingen. Cuvillier Verlag Göttingen.

Sauer, U., R.-J. Fischer und P. Dürre. 1993. Solvent formation and its regulation in strictly anaerobic bacteria. In: Current topics in molecular genetics (J. Menon, Hrsg.), S. 337-351.

Fischer, R.-J., J. Helms, P. Dürre. 1993. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis. J. Bacteriol. 175: 6959-6969