2024

Loeffler H, Waletzko-Hellwig J, Fischer R-J, Basen M, Frank M, Jonitz-Heincke A, Bader R, Klinder A. 2024. Systematic enhancement of microbial decontamination efficiency in bone graft processing by means of high hydrostatic pressure using Escherichia coli as a model organism. J Biomed Mater Res 112:e35383. https://doi.org/10.1002/jbm.b.35383
 

2014 - 2016

Breitkopf, R., R. Uhlig, T. Drenckhan, R.-J. Fischer. 2016. Two propanediol utilization-like proteins of Moorella thermoacetica with phosphotransacetylase activity. Extremophiles. DOI: 10.1107/s00792-016-0854-6

Uhlig, R., A. Poehlein, R.-J. Fischer, R. Daniel, H. Bahl. 2016. Genome sequence of the autotrophic acetogen Clostridium magnum DSM 2767. Genome Announc 4(3): e00464-16. DOI: 10.1128/genomeA.00464-16

Hoffmeister, S., M. Gerdom, F. R. Bengelsdorf, S. Linder, S. Flüchter, H. Öztürk, W. Blümke, A. May, R.-J. Fischer, H. Bahl, P. Dürre. 2016. Acetone production with metabolically engineered srains of Acetobacterium woodii. Metabolic Engineering 36:37-47. DOI: 10.1016/j.ymben.2016.03.001

Wetzel, D., R.-J. Fischer. 2015. Small acid-soluble spore proteins of Clostridium acetobutylicum are able to protect DNA in vitro and are specifically cleaved by germination protease GPR and spore protease YyaC . Microbiology 161:2098-2109 DOI: 10.1099/mic.0.000162.

Millat, T., C. Voigt, H. Janssen, C. M. Cooksley, K. Winzer, N. P. Minton, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2014. Coenzyme A-transferase-independent butyrate reassimilation in Clostridium acetobutylicum - evidence from a mathematical model. Appl Microbiol Biotechnol 98:9059-9072 DOI: 10.1007/s00253-014-5987-x

Voigt,C., H. Bahl, R.-J. Fischer. 2014. Identification of PTSFru as the major fructose uptake system of Clostridium acetobutylicum. Appl Microbiol Biotechnol 98:7161-7172 DOI: 10.1007/s00253-014-5809-1
 

2011 - 2013

Millat, T., H. Janssen, G. J. Thorn, J. R. King, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2013. A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicum in phosphate-limited continuous cultures. Appl Microbiol Biotechnol 97:6451-6466 DOI: 10.1007/s00253-013-4860-7

Millat, T., H. Janssen, H. Bahl, R.-J. Fischer, O. Wolkenhuer. 2013. The pH-induced metabolic shift from acidogenesis to solventogenesis in Clostridium acetobutlicum - From experiments to models. In: Kettner, C. and Hicks, M. G., eds., Proceedings of the 5th International Beilstein Symposium on Experimental Standard Condtions of Enzyme Characterizations Logos Verlag Berlin. 33-53.

Millat, T., H. Janssen, H. Bahl, R.-J. Fischer, O. Wolkenhauer. 2013. Integrative modelling of pH-dependent enzyme activity and transcriptomic regulation of the acetone-butanol-ethanol fermentation of Clostridium acetobutylicum in continous culture. Microbial Biotechnology, DOI: 10.1111/1751-7915.12033

May, A., R.-J. Fischer, S. M. Thum, S. Schaffer, S. Verseck, P. Dürre, H. Bahl. 2013. A modified pathway for the production of acetone in Escherichia coli. Metabolic Engineering 15: 218-225 http://dx.doi.org/10.1016/j.ymben.2012.08.001

Janssen, H., T. Fiedler, K. Schwarz, H.Bahl, R.-J. Fischer. 2012. Supporting systems biology of Clostridium acetobutylicum by proteome analysis. In: Systems Biology of Clostridium. (P. Dürre, Ed.), Imperial College Press., 56-84

Janssen, H., C. Grimmler, A. Ehrenreich, H. Bahl, R.-J. Fischer. 2012. A transcriptional study of acidogenic chemostat cells of Clostridium acetobutylicum - Solvent stress caused by a transient n-butanol pulse. J Biotec. http://dx.doi.org/10.1016/j.jbiotec.2012.03.027

Haus, S., S. Jabbari, T. Millat, H. Janssen, R.-J. Fischer, H. Bahl, J. R. King, O. Wolkenhauer. 2011. A Systems Biology Approach to Investigate the Effect of pH-induced Gene Regulation on Solvent Production by Clostridium acetobutylicum in Continous Culture. BMC Systems Biology 5:10 (DOI:10.1186/1752-0509-5-10)

Millat, T., O. Wolkenhauer, R.-J. Fischer, H. Bahl. 2011. Modeling of Cellular Processes: Methods, Data, and Requirements. In: M. Hamacher et al. (eds.), Data Mining in Proteomics: From Standards to Applications, Methods in Molecular Biology, Vol. 696, DOI 10.1007/978-1-60761-987-1_27, Springer Science+Business Media, LLC 2011

Grimmler, C., H. Janssen, D. Krauße, R.-J. Fischer, H. Bahl, P. Dürre, W. Liebl, A. Ehrenreich. 2011: Genome-wide Gene Expression Analysis of the Switch between Acidogenesis and Solventogenesis in Continuous Cultures of Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol., 20:1-15 (DOI: 10.1159/000320973)

2008 - 2010

Janssen, H., C. Döring, A. Ehrenreich, B. Voigt, M. Hecker, H. Bahl, R.-J. Fischer. 2010: A proteomic and transcriptional view of acidogenic and solventogenic steady state cells of Clostridium acetobutylicum in a chemostat culture. Appl. Microbiol. Biotechnol., 87: 2209

Hillmann, F., Döring, C., Ehrenreich, A., Fischer, R.-J., Bahl, H. 2009. The role of PerR in O2 affected gene expression of Clostridium acetobutylicum. J. Bacteriol., 191: 6082-6093

Hillmann, F., Riebe, O., Fischer, R.-J., Mot, A., Caranto, J. D., Kurtz, Jr., D. M., Bahl. H. 2009. Reductive dioxygen scavenging by flavo-diiron proteins of Clostridium acetobutylicum.
FEBS Lett. 583:241-245

Riebe, O., R.-J. Fischer, D. A. Wampler, D. M. Kurtz, Jr., H. Bahl. 2009. Pathway for H2O2 and O2 detoxification in Clostridium acetobutylicum. Microbiology 155:16-24

Fiedler, T., M. Mix, U. Meyer, S. Mikkat, M. O. Glocker, H. Bahl, R.-J. Fischer. 2008. The two component system PhoP/R of Clostridium acetobutylicum is involved in phosphate dependent gene
regulation. J. Bacteriol. 190: 6559-6567

Harndorf, H., B. Bahl, R.-J. Fischer, E. Flügge, U. Schümann, V. Wichmann. 2008. Untersuchungen der Mutagenität von Motorabgasen an einem Euro IIIa Traktormotor im Diesel-, Biodiesel-, und Rapsölbetrieb. Raps 4/2008: 212-214

Hillmann, F., Fischer, R.-J., Saint-Prix, F., Girbal, L., Bahl, H. 2008. PerR acts as a switch for oxygen tolerance in the strict anaerobe Clostridium acetobutylicum. Mol. Microbiol. 68: 848-860

2000 - 2007

Riebe, O., Fischer, R.-J., Bahl, H. 2007. Desulfoferrodoxin of Clostridium acetobutylicum functions as a superoxide reductase. FEBS Lett. 581: 5605-5610

Schwarz, K., T. Fiedler, R.-J. Fischer, H. Bahl. 2007. A Standard Operating Procedure (SOP) for the preparation of intra- and extracellular proteins of Clostridium acetobutylicum for proteome analysis. J. Microbiol. Meth. 68: 396-402

Fischer, R.-J., Oehmcke, S., Meyer, U., Mix, M., Schwarz, K., Fiedler, T., Bahl, H. 2006. Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH. J. Bacteriol. 188: 5469-5478

Hillmann, F., Fischer, R.-J., Bahl, H. 2006. The rubrerythrin-like protein Hsp21 of Clostridium acetobutylicum is a general stress protein. Arch. Microbiol.185 (4): 270-276

May, A., T. Pusztahelyi, N. Hoffmann, R.-J. Fischer, H. Bahl. 2006. Site-directed mutagenesis of conserved amino acids in SLH domains of Thermoanaerobacterium thermosulfurigenes EM1 effects attachment to cell wall sacculi. Arch. Microbiol.185 (4): 263-269

Fischer, R.-J., Bahl, H. 2005. Transport of phosphate. In: Dürre, P. (Ed.). Handbook on Clostridia. CRC Press, Boca Raton, Florida, USA.

May, A., Hillmann, F., Riebe, O., Fischer, R.-J., Bahl, H. 2004. A rubrerythrin-like oxidative stress protein of Clostridium acetobutylicum is encoded by a duplicated gene and identical to the heat shock protein Hsp21. FEMS Microbiol. Lett. 238: 249-254

Behrens, S., U. Meyer, H. Schankin, M. A. Lonetto, R.-J. Fischer, H. Bahl. 2000. Identification of two genes encoding putative new members of the ECF subfamily of eubacterial RNA polymerase sigma factors in Clostridium acetobutylicum. J. Mol. Microbiol. Biotechnol. 2(3): 265-269

1993 - 1995

Dürre, P., R.-J. Fischer, A. Kuhn, K. Lorenz, W. Schreiber, B. Stürzenhofecker, S. Ullmann, K. Winzer und U. Sauer. 1995. Solventogenic enzymes of Clostridium acetobutylicum: Catalytic properties, genetic organization, and transcriptional regulation. FEMS Microbiol. Rev. 17: 251-262.

Fischer, R.-J., U. Sauer und P. Dürre. 1994. Regulation of solvent formation in Clostridium acetobutylicum. In: Progress in Biotechnology 9, ECB6: Proceedings of the 6th European Congress on Biotechnology, Florence, Italy, June 13-17, 1993 (L. Alberghina, L. Frontali, P. Sensi, Hrsg.), Elsevier Science B. V., Amsterdam. S. 337-340.

Fischer, R.-J. 1994. Klonierung, Sequenzierung, molekulare Charakterisierung und Mutagenese von Genen der Lösungsmittelbildung aus Clostridium acetobutylicum. Dissertation, Universität Göttingen. Cuvillier Verlag Göttingen.

Sauer, U., R.-J. Fischer und P. Dürre. 1993. Solvent formation and its regulation in strictly anaerobic bacteria. In: Current topics in molecular genetics (J. Menon, Hrsg.), S. 337-351.

Fischer, R.-J., J. Helms, P. Dürre. 1993. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis. J. Bacteriol. 175: 6959-6969